New discoveries in quest for better drugs
1st December 2013
Two studies into alternative drug recognition sites on G protein-coupled receptors have been published in Nature. Scientists have combined cutting edge computer modelling, structural biology, pharmacology and medicinal chemistry to reveal new insights into how the body interacts with novel drug treatments, in research that could lead to the creation of drugs that are more targeted and with fewer side effects.
In two papers published recently in Nature, researchers from the Monash Institute of Pharmaceutical Sciences (MIPS) were part of an international team who investigated alternative drug recognition sites on G protein-coupled receptors (GPCRs) – the largest and most important family of receptor proteins in the human body.