Benefits of statin therapy may extend beyond lowering lipids
30th December 2013
People with high cholesterol are at risk of heart attack and stroke because atherosclerotic plaques within their arteries can rupture triggering the formation of a blood clot called an occlusive thrombus that cuts off the blood supply to their heart or brain.
For years, scientists have studied the cause of this abnormal clotting. Now, a study led by researchers from the University of North Carolina at Chapel Hill School of Medicine, has identified a molecular pathway that leads to this abnormal blood clotting and turned it off using a popular class of cholesterol-lowering drugs, statins.