Researchers identify novel compound effective against drug-resistant lung cancer

15th April 2014

Despite advances made in detecting and treating nonsmall cell lung cancer , its prognosis remains grim.Even patients whose cancers are caught at their earliest stage have only a 50 percent chance of five-year survival.This poor prognosis is due in part to the cancer ‘s ability to resist treatment, rendering the chemotherapy ineffective.

However, a group of City of Hope researchers have identified and synthesized a novel compound — called COH-SR4 — that is effective against drug-resistant lung cancer.If its safety and efficacy pan out in future studies, COH-SR4 could play a vital role in treating lung cancers that no longer respond to first-line chemotherapy.

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