Study Suggests Link Between Viagra And Melanoma

12th April 2014

In recent years researchers have uncovered a potentially important pathway whereby PDE5A inhibitors (which include sildenafil– Viagra– and other drugs used to treat erectile dysfunction and pulmonary hypertension) could potentially increase the risk of developing melanoma. Now a new study provides early evidence showing an association between sildenafil and melanoma, though, like all observational studies, it is unable to demonstrate a cause-and-effect relationship.

The study, published in JAMA Internal Medicine, analyzed data from more than 25,000 men who participated in the Health Professionals Follow-up Study. Men who had recently used sildenafil had nearly twice the risk of developing melanoma after adjusting for other risk factors (hazard ratio 1.84, CI 1.04 – 3.22). Men who had used sildenafil at any time had a similar increase in risk. No increase in risk was observed for other skin cancers (basal cell carcinoma and squamous cell carcinoma) without known links to PDE5A inhibitors. In addition, there was no significant association between erectile function by itself and melanoma.

Read more at source article: www.forbes.com 


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